Gosselink et al 10 conducted a systematic review with meta-analysis, including 32 randomized controlled trials (RCTs) on IMT effects in subjects with COPD. 8 As a pulmonary rehabilitation strategy, inspiratory muscle training (IMT) optimizes lung capacity and, consequently, improves physical conditioning. 6, 7 Thus, pulmonary rehabilitation is recommended as an efficient intervention in cardiorespiratory management, generating improvements in exercise performance, with reductions in dyspnea in patients with different degrees of disease severity. 5 Inspiratory muscle dysfunction also occurs in these patients and is associated with dyspnea and reduced exercise capacity. Individuals with COPD present with limitations in exercise capacity due to multiple factors, including ventilation, gas exchange, cardiovascular disease, 4 and abnormalities in peripheral muscles.
2 Strategies are required that aim to reduce the disease progression and thus improve patients’ prognosis as well as reduce costs of health care and the global and socioeconomic burden of the disease. 1 Prognosis of patients with COPD is influenced by the severity and recurrence of exacerbation, with yearly mortality rates of 11% for patients who need hospitalization, 5–50% for patients on mechanical ventilation, and rising as high as 37% in case of hospitalization for exacerbation recurrence.
COPD is one of the major causes of chronic morbidity and mortality worldwide.
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